01
What is NAD+? The magical molecule that deeply unlocks cell vitality
NAD+， Nicotinamide adenine dinucleotide is a key metabolite and coenzyme present in every cell of the human body.
02
What is NAD+ and why is it so critical to health and longevity?
NAD+represents nicotinamide adenine dinucleotide. From single celled organisms such as bacteria to complex multicellular organisms such as primates, NAD+is one of the most abundant and critical molecules.
03
Telomeres are quietly making you age - In-depth research on telomeres
Three scientists, Elizabeth Blackburn, Carol Greider, and Jack Szostak, won the Nobel Prize in Physiology or Medicine in 2009 for their discovery of how telomeres and telomerase protect chromosomes. Since then, the trend of research and development between telomeres and aging has been unstoppable.
04
Everyone has cancer cells! You don’t know how hard your telomeres work to prevent cells from becoming cancerous!
Telomeres are the caps at both ends of chromosomes, like plastic tips at the end of shoelaces, protecting chromosomes from degradation and scattering. As age increases, the number of cell divisions increases, telomeres gradually deplete, and their length shortens.
05
EMBO reports | Telomere DNA damage promotes transcription of SARS-CoV-2 receptor ACE2 during aging
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of COVID-19 epidemic in 2019. Recent studies have emphasized the important role of human angiotensin-converting enzyme 2 (ACE2) molecules in mediating the cellular entry of SARS-CoV-2. The binding to ACE2 receptors is a crucial initial step in SARS-CoV-2 infection of target cells and is crucial for human infection, and the e
06
Nature Aging: Extend lifespan by 40%! French scientists discover that intestinal-specific telomerase expression can extend telomeres and slow systemic aging
Telomeres are the terminal structures of linear chromosomes in eukaryotic cells, playing a protective role during cell replication, avoiding DNA damage, and effectively preventing end recombination, fusion, and chromosomal degeneration between chromosomes like a hat
07
Short telomeres increase mortality by 76%! A study of more than 470,000 people reveals the mystery of telomeres and disease death. Big data will help you rewrite the
Everything in the world has measurements, from the size of cells to the length of life. In this article, the protagonist we will introduce is the "cellular life clock" that measures the length of life, telomeres.
08
New discovery! Prospective study of more than 26,000 people: These factors are significantly associated with dementia, which may provide prevention methods!
Dementia is a chronic or progressive syndrome that can lead to cognitive decline and fragmented abilities in memory, thinking, understanding, and language. With the development of the economy and the intensification of the aging process, according to data from the World Health Organization (WHO), the number of dementia patients worldwide exceeds 55 million, and there are also 10 million newly conf
09
Science | The secret of longevity - systematically identifying genes associated with longevity
Aging is a comprehensive and gradual decline in physical fitness, intellectual level, and reproductive ability, accompanied by the occurrence of various diseases and an increase in mortality. However, the current comprehensive understanding of the interaction between genetics, gender, and environment in aging and gender determination is still limited
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Science sub-journal: Umbilical cord blood really contains "young factors"! Chinese scientists have discovered that extracellular vesicles derived from umbilical cord blood can comprehensively improve
In order to combat aging, humans have come up with countless methods, among which the craziest one is "reversing aging with blood transfusion". This story can be described as ups and downs with suspense. However, is there really a so-called "youthful factor" in the blood of young people? In 2017, Tony Wyss Coray's team found TIMP2 protein in umbilical cord blood that could improve brain function.